Table 1

Children assessed at age 2 years: the maternal baseline characteristics at randomization to treatment in MiG

Metformin (n = 154)Insulin (n = 164)P value
Age (years)39.4 ± 5.238.9 ± 50.32
BMI (kg/m2)
 At booking (before 20 weeks’ gestation)31.8 ± 8.231.1 ± 100.47
 At recruitment33.4 ± 1231.6 ± 100.12
 Gestational age at recruitment (weeks)30.4 ± 3.330.0 ± 3.30.58
Ethnicity (self-reported)0.46
 European/Caucasian88 (57.1)78 (47.6)
 Polynesian21 (13.6)26 (15.9)
 Indian22 (14.3)34 (20.7)
 Chinese and other Southeast Asian15 (9.7)16 (9.8)
 Other or mixed8 (5.2)10 (6.1)
Tertiary education79 (51.3)96 (58.5)0.24
Smoking in pregnancy16 (10.4)10 (6.1)0.23
Chronic hypertension20 (13.0)17 (10.4)0.58
75-g OGTT result
 Fasting plasma glucose (mmol/L)5.5 ± 15.6 ± 10.56
 2-h plasma glucose(mmol/L)9.6 ± 29.5 ± 20.72
 HbA1c at recruitment (%)5.7 ± 0.585.7 ± 0.670.96
  • Data expressed as mean ± SD or n (%). OGTT, oral glucose tolerance test.