Table 2

Crude cancer events during follow-up: overall and in the highest–daily insulin dose quartile

TotalGlargine insulinNonglargine insulinCombinationP for difference across groups
Overall
 Any5,466 (39.1)1,147 (38.8)3,345 (39.4)974 (38.4)0.755
 Breast553 (5.2)118 (5.6)333 (5.1)102 (5.4)0.623
 Colon428 (2.8)70 (2.1)281 (3.0)77 (2.7)0.035
 Pancreas204 (1.3)47 (1.4)128 (1.3)29 (1.0)0.324
 Prostate427 (9.8)117 (10.9)244 (8.0)66 (9.8)0.130
Highest–daily insulin dose quartile
 Any1,352 (39.4)164 (40.2)1,031 (39.6)157 (37.5)0.784
 Breast130 (5.0)14 (4.8)93 (4.6)23 (7.2)0.155
 Colon113 (3.0)ID92 (3.2)ID0.037
 Pancreas40 (1.0)IDIDID−0.584
 Prostate94 (9.1)IDIDID0.321
  • Data are N (rate per 1,000 person-years). For the highest–daily dose quartile, N = 20,415. ID, insufficient data for reporting under regulations of the Centers for Medicare & Medicaid Services. Difference across groups was assessed with log-rank tests. The Centers for Medicare & Medicaid Services does not permit reporting of cell counts <11 or, cell counts permitting, by extrapolation, inference about cells with counts <11.