Table 2

Average mean CCA-IMT and average annual mean CCA-IMT progression in people with and without diabetes

Average mean CCA-IMT (mm)Average annual mean CCA-IMT progression (mm/year)
CohortDiabetes, mean (SD)No diabetes, mean (SD)Difference, mean (SE)&Diabetes, mean (SD)No diabetes, mean (SD)Difference, mean (SE)&
AIR0.86 (0.14)0.79 (0.12)0.066 (0.036)−0.004 (0.040)0.001 (0.028)−0.005 (0.008)
ARIC0.72 (0.13)0.56 (0.11)0.052 (0.003)0.009 (0.048)0.011 (0.037)−0.001 (0.001)
CAPS0.81 (0.13)0.73 (0.17)0.018 (0.018)−0.004 (0.035)0.003 (0.092)−0.007 (0.011)
CHS10.90 (0.16)0.86 (0.14)0.038 (0.005)0.006 (0.053)0.005 (0.045)0.001 (0.002)
CHS20.94 (0.15)0.92 (0.16)0.015 (0.020)0.005 (0.030)0.011 (0.028)−0.007 (0.004)
CMCS0.85 (0.23)0.81 (0.19)0.040 (0.025)0.037 (0.044)0.040 (0.041)−0.002 (0.006)
DIWA0.94 (0.17)0.86 (0.15)0.074 (0.025)−0.001 (0.022)0.004 (0.020)−0.005 (0.003)
EAS0.87 (0.20)0.85 (0.19)0.005 (0.033)0.030 (0.032)0.030 (0.045)0.001 (0.008)
EPICARDIAN0.78 (0.15)0.79 (0.21)−0.004 (0.079)−0.093 (0.101)−0.099 (0.133)0.001 (0.052)
EVA0.72 (0.11)0.66 (0.10)0.045 (0.014)0.008 (0.040)0.006 (0.046)0.002 (0.006)
INVADE0.86 (0.18)0.81 (0.17)0.031 (0.008)0.012 (0.082)0.009 (0.075)0.004 (0.004)
KIHD0.83 (0.12)0.81 (0.16)0.010 (0.027)0.024 (0.022)0.028 (0.033)−0.005 (0.006)
NOMAS/INVEST0.72 (0.09)0.73 (0.08)−0.005 (0.008)0.007 (0.028)0.009 (0.030)−0.002 (0.003)
PIVUS0.97 (0.17)0.92 (0.14)0.049 (0.021)0.009 (0.034)0.009 (0.029)0.000 (0.004)
PLIC0.74 (0.12)0.66 (0.13)0.029 (0.013)0.009 (0.032)0.015 (0.036)−0.007 (0.004)
Rotterdam0.86 (0.15)0.79 (0.14)0.046 (0.011)0.012 (0.024)0.012 (0.021)0.000 (0.002)
SAPHIR0.91 (0.11)0.80 (0.12)0.074 (0.019)0.024 (0.024)0.017 (0.019)0.005 (0.003)
SHIP0.83 (0.16)0.78 (0.14)0.031 (0.009)0.009 (0.037)0.003 (0.023)0.001 (0.002)
Tromsø0.87 (0.16)0.78 (0.14)0.053 (0.013)0.010 (0.034)0.004 (0.019)0.006 (0.002)
Combined (95% CI)*0.82 (0.17)0.71 (0.18)0.041 (0.036–0.045)0.009 (0.052)0.010 (0.047)−0.000 (−0.001 to 0.001)
  • Mean CCA-IMT is not available in Bogalusa Heart Study (BHS), Bruneck study (Bruneck), or the Chin-Shan Community Cardiovascular Cohort (CCCC). AIR, Atherosclerosis and Insulin Resistance study; CMCS, Chinese Multi-provincial Cohort Study; DIWA, Diabetes, Impaired glucose tolerance in Women and Atherosclerosis; EAS, Edinburgh Artery Study; EPICARDIAN, Estudio epidemiológico sobre enfermedades y factores de riesgo cardiovasculares en ancianos españoles; KIHD, Kuopio Ischaemic Heart Disease study; PIVUS, Prospective Investigation of the Vasculature in Uppsala Seniors; PLIC, Progression of Lesions in the Intima of the Carotid; Rotterdam, Rotterdam Study; SAPHIR, Salzburg Atherosclerosis Prevention program in subjects at High Individual Risk; Tromsø, Tromsø Study.

  • &Adjusted for age and sex by multiple regression.

  • *Combined means and SDs weighted by sample size; differences between people with and without diabetes combined by random-effects meta-analysis.