Table 3

Logistic regression analysis showing risk of excess offspring adiposity with maternal gestational OGTT glucose and GDM status

Offspring
BMI z scoreSum of skinfolds ≥90th percentile
(n = 1,310)
≥85th percentile
(n = 1,316)≥95th percentile
(n = 1,316)≥99th percentile
(n = 1,316)
FPG
 Unadjusted2.01 (1.37–2.96)2.37 (1.41–3.98)4.32 (2.07–9.04)2.48 (1.44–4.26)
 Adjusted model*1.16 (0.76–1.76)1.34 (0.76–2.35)2.32 (1.05–5.13)1.61 (0.90–2.89)
1-h PG unadjusted1.06 (0.98–1.15)1.01 (0.91–1.13)1.06 (0.90–1.24)1.02 (0.91–1.14)
2-h PG unadjusted1.10 (0.99–1.23)0.99 (0.85–1.15)0.94 (0.75–1.18)0.99 (0.84–1.16)
AUC PG unadjusted1.06 (1.00–1.13)1.02 (0.93–1.11)1.04 (0.92–1.18)1.02 (0.93–1.12)
GDM
 Unadjusted1.62 (1.17–2.25)1.56 (1.01–2.41)1.37 (0.72–2.63)1.30 (0.81–2.09)
 Adjusted model*1.18 (0.84–1.67)
  • Data are OR (95% CI) for one unit rise in OGTT glucose measures and for GDM (excluding unblinded participants) compared with no GDM. Sex-specific cutoffs were used for the sum of skinfolds ≥90th percentile.

  • *Adjusted for maternal OGTT BMI and offspring birth weight z score.

  • P < 0.001.

  • P < 0.01.