Table 1

Subject inclusion/exclusion criteria for cohorts

Cohort 1: single autoantibodyCohort 2: multiple autoantibodiesCohort 3: dysglycemia
1) Single-autoantibody positivity of mIAA, GAD65Ab, or IA-2A at initial screening and confirmed positivity of the same type of autoantibody on another occasion1) Two or more positive autoantibodies of mIAA, GAD65Ab, IA-2A, ICA, or ZnT8Ab at any screening or follow-up visit1) One or more positive autoantibodies of mIAA, GAD65Ab, IA-2A, ICA, or ZnT8Ab at the time of abnormal OGTT results
2) Normal baseline OGTT result2) Normal baseline OGTT result2) At least one abnormal OGTT result