Table 4

The effects of medical therapies in the sensitivity analyses conducted with interval-censored Cox proportional hazards models using both year 4 and year 8 data

Only participants with year 8 dataAll participants (those with years 4 or 8 data)ACCORDION (death as a competing risk)
n/N (%)Adjusted HR (95% CI)P valuen/N (%)Adjusted HR (95% CI)P valuen/N (%)Adjusted HR (95% CI)P value
Glycemia therapy0.45 (0.32–0.64)<0.00010.56 (0.44–0.71)<0.00010.58 (0.46–0.73)<0.0001
 Intensive49/658 (7.4)106/1,437 (7.4)336/1,541 (21.8)
 Standard102/652 (15.6)183/1,442 (12.7)428/1,541 (27.8)
Dyslipidemia therapy0.84 (0.57–1.24)0.380.76 (0.57–1.03)0.080.83 (0.69–1.00)0.04
 Simvastatin/fenofibrate50/399 (12.5)78/815 (9.6)219/870 (25.2)
 Simvastatin/placebo50/363 (13.8)93/796 (11.7)238/861 (27.6)
Antihypertensive therapy1.23 (0.70–2.14)0.471.05 (0.73–1.51)0.790.95 (0.76–1.20)0.68
 Intensive29/280 (10.4)62/650 (9.5)153/688 (22.2)
 Standard22/268 (8.2)56/618 (9.1)154/663 (23.2)