Table 1

Baseline characteristics of ACCORD Eye Study participants who consented and were eligible for the ACCORDION Eye Study

Not in ACCORDION analysis (n = 2,162)In ACCORDION analysis (n = 1,310)P value
Age (years)61.9 ± 6.961.3 ± 5.80.0235
Diabetes duration (years)10.1 ± 7.39.9 ± 6.80.3652
Female sex840 (38.9)493 (37.6)0.4740
Previous cardiovascular event762 (35.2)361 (27.6)<0.0001
Nonwhite race733 (33.9)345 (26.3)<0.0001
Glycated hemoglobin (%) (mmol/mol)8.3 ± 1.1 (65 ± 10.9)8.2 ± 1.0 (67 ± 12.0)<0.0001
HDL cholesterol (mg/dL)42.1 ± 11.541.7 ± 10.60.3365
LDL cholesterol (mg/dL)103.0 ± 33.499.2 ± 32.70.0010
Triglycerides (mg/dL)198.6 ± 163.6190.6 ± 152.30.1506
Systolic BP (mmHg)135.9 ± 17.3133.1 ± 16.4<0.0001
Diastolic BP (mmHg)75.2 ± 10.874.7 ± 10.40.1651
Urinary albumin-to-creatinine ratio94.6 ± 312.148.7 ± 164.1<0.0001
BMI (kg/m2)32.6 ± 5.532.3 ± 5.40.1487
Visual acuity (Snellen equivalent)74.8 ± 10.7 (20/30)76.8 ± 9.7 (20/30)<0.0001
Smoking status0.0007
 Never smoked842 (38.9)573 (43.8)
 Previous smoker987 (45.7)588 (44.9)
 Current smoker333 (15.4)148 (11.3)
Diabetic retinopathy status0.0121
 None1,036 (48.8)687 (52.4)
 Mild377 (17.8)251 (19.2)
 Moderate NPDR675 (31.8)362 (27.6)
 Severe NPDR7 (0.3)3 (0.2)
 PDR28 (1.3)7 (0.5)
  • Data are presented as mean ± SD or as n (%).

  • NPDR, nonproliferative diabetic retinopathy; PDR, proliferative diabetic retinopathy.