Table 3

Mean glucose levels and time in target for inpatient CL admissions

CL aloneCL + adjunctive therapyP value
Pramlintide
 Daytime (8:00 a.m.–11:00 p.m.)
  Mean blood glucose (mg/dL)166 ± 47160 ± 400.08
  <70 mg/dL1.90.3
  70–180 mg/dL59.771.10.004
  >180 mg/dL38.428.5
 Nocturnal (11:00 p.m.–6:00 a.m.)
  Mean blood glucose (mg/dL)121 ± 20122 ± 280.87
  <70 mg/dL02.7
  70–180 mg/dL98.793.30.12
  >180 mg/dL1.34
Liraglutide
 Daytime (8:00 a.m.–11:00 p.m.)
  Mean blood glucose (mg/dL)143 ± 55146 ± 470.13
  <70 mg/dL5.93.3
  70–180 mg/dL71.674.40.50
  >180 mg/dL22.422.3
 Nocturnal (11:00 p.m.–6:00 a.m.)
  Mean blood glucose (mg/dL)104 ± 23113 ± 240.0001
  <70 mg/dL5.52.4
  70–180 mg/dL94.596.40.13
  >180 mg/dL01.2
  • Data are mean ± SD for glucose levels and percent of time in various ranges (<70, 70–180, and >180 mg/dL). System target glucose was 120 mg/dL for the pramlintide study and 100 mg/dL for the liraglutide study.