Table 1

Patient demographics and baseline characteristics

Buprenorphine (n = 93)Placebo (n = 93)
Age (years)62.6 (9.6)63.3 (9.3)
Male sex67.765.6
Race
 Caucasian95.792.5
 Asian1.11.1
 Other3.26.4
Weight (kg)95.8 (18.2)100.3 (19.3)
Height (cm)173.4 (9.1)172.1 (8.3)
HbA1c (%)7.56 (1.57)7.79 (1.43)
Diabetes medications
 Acarbose02.2
 Metformin79.672.0
 Sulfonylurea28.024.7
 Insulin62.479.6
 Thiazolidinedione7.510.8
 Sitagliptin2.27.5
NRS pain score5.7 (1.1)5.9 (1.3)
MNSI score6.0 (1.5)6.1 (1.5)
Concomitant adjuvant use
 Antidepressant36.635.5
 Antiepileptic24.732.3
  • Data are mean (SD) or %. MNSI, Michigan Neuropathy Screening Instrument.