Table 1

Distribution of PFOS and PFOA and indicators of adiposity and glucose metabolism in childhood, adolescence, and young adulthood

Childhood (1997)Adolescence (2003)Adulthood (2009)
MalesFemalesMalesFemalesMalesFemales
NMedian (IQR)NMedian (IQR)NMedian (IQR)NMedian (IQR)NMedian (IQR)NMedian (IQR)
Age (years)2799.7 (9.4; 10.0)3119.6 (9.3; 9.9)19315.8 (15.6; 16.0)25115.7 (15.4; 16.0)17121.8 (21.6; 22.1)19821.8 (21.4; 22.0)
PFOS (ng/mL)23644.5 (35.4; 55.7)26539.9 (34.3; 49.3)9122.3 (16.5; 25.1)11020.8 (15.9; 24.7)9211.9 (9.2; 15.2)1109.1 (7.0; 10.8)
PFOA (ng/mL)2369.7 (7.7; 12.1)2659.0 (7.4; 11.2)913.7 (2.7; 4.4)1103.4 (2.8; 4.5)923.1 (2.5; 3.9)1102.7 (2.1; 3.4)
BMI (kg/m2)27916.9 (15.7; 18.4)31116.7 (15.4; 18.6)19320.7 (19.1; 22.1)25120.7 (19.4; 22.9)17124.1 (22.1; 26.3)19822.5 (20.9; 25.4)
Skinfold thickness (mm)26828.8 (23.0; 38.9)30533.2 (26.4; 46.0)19327.5 (22.6; 37.1)25149.2 (39.9; 61.7)17144.3 (35.5; 64.8)19566.3 (52.5; 80.9)
Waist circumference (cm)27258.0 (55.3; 61.5)31157.0 (54.3; 60.8)19274.4 (70.1; 78.2)25171.0 (68.3; 75.7)17182.8 (75.0; 89.8)19875.0 (70.2; 80.5)
Insulin (pmol/L)24541.5 (28.5; 56.4)27448.4 (36.6; 64.6)19053.2 (39.7; 71.3)24460.1 (43.8; 75.2)16735.2 (23.0; 52.8)19545.9 (36.0; 65.9)
HOMA-β24573.7 (61.0; 91.0)27488.2 (71.3; 103.7)19089.6 (75.6; 107.2)244105.0 (86.9; 128.7)16768.2 (53.7; 88.8)19490.8 (79.3; 106.8)
HOMA-IR2450.8 (0.5; 1.1)2740.9 (0.7; 1.2)1901.0 (0.7; 1.3)2441.1 (0.8; 1.4)1670.7 (0.4; 1.0)1940.9 (0.7; 1.2)
Glucose (mmol/L)2475.2 (4.9; 5.4)2785.0 (4.8; 5.3)1905.2 (4.9; 5.4)2444.9 (4.6; 5.1)1695.2 (4.8; 5.4)1954.9 (4.6; 5.2)
Triglyceride (mmol/L)2470.7 (0.6; 0.9)2780.8 (0.6; 1.1)1900.7 (0.5; 0.9)2440.7 (0.5; 1.0)1691.1 (0.7; 1.4)1951.1 (0.9; 1.4)
  • IQR, interquartile range.