Table 1

Characteristics of TrialNet autoantibody-positive subjects (n = 1,287)

CharacteristicsAb+ subjects without diabetes (n = 1,110)Ab+ subjects with diabetes (n = 177)P value
Age at initial visit (years)16 (9–37)10 (7–14)<0.0001
Age at last visit (years)19 (12–39)11 (8–17)<0.0001
Sex, female669 (60)88 (50)0.02
Multiple (≥2) Ab+ at initial visit249 (22)136 (77)<0.0001
HLA DR3/4-DQ8 (yes)71 (15)33 (25)0.007
BMI at initial visit (% underweight/normal/overweight/obese)1/57/22/202/62/18/180.35
  • Data are median (IQR) or n (%), unless specified otherwise. Boldface type indicates P < 0.05. Ab+, autoantibody positive.