Table 2

Crude incidence rates and adjusted HRs for thromboembolic events in women with diabetes by contraception use at the time of the TE stratified by age

Number of TEs/woman-yearsThrombosis per 1,000 woman-years of useAdjusted HR* (95% CI)
EstrogenProgestinNoneEstrogenProgestinNoneEstrogen vs. no hormonalProgestin vs. no hormonalProgestin vs. estrogen
<35 years300/29,98850/6,905650/189,48110.07.23.43.38 (2.94–3.88) (P < 0.0001)2.02 (1.51–2.70) (P < 0.0001)0.60 (0.44–0.81) (P = 0.0009)
≥35 years186/15,79845/4,4881,781/231,98811.810.07.71.79 (1.54–2.09) (P < 0.0001)1.33 (0.99–1.79) (P = 0.0593)0.74 (0.54–1.03) (P = 0.0741)
  • TE, thromboembolism.

  • *Adjusted for age, advanced diabetes, hyperlipidemia, hypertension, cancer, obesity, and smoking.