N | Prevalence of monogenic diabetes | PPV (%) | NPV (%) | Percentage of monogenic cases missed | Number needed to test | |
---|---|---|---|---|---|---|

Biomarker pathway | 1,407 | 3.6% (51/1,407) | 20.0 | 99.91 | 0 | 5 |

Traditional MODY criteria | 1,362 | 3.6% (49/1,362) | 57.6 | 97.7 | 63 | 2 |

MODY probability calculator | 1,347 | 3.3% (45/1,347) | 40.4 | 98.3 | 55 | 3 |

Prevalence is the proportion of diagnosed monogenic diabetes, percentage of monogenic cases missed is the proportion of monogenic cases not picked up by the approach, and number needed to test is 1/PPV.