Table 2

Adjusted HRs and 95% CIs for traditional risk factors for severe hypoglycemia (n = 1,206; 185 people with hypoglycemia)

Model 1Model 2
Age, per 5 years1.42 (1.25–1.62)1.24 (1.07–1.43)
Female sex0.96 (0.71–1.30)1.09 (0.80–1.48)
Black race1.92 (1.42–2.60)1.39 (1.02–1.88)
Obese*1.46 (1.07–1.97)1.31 (0.96–1.78)
Fructosamine (vs. lowest tertile)
 Middle tertile (296–350 μmol/L)2.30 (1.46–3.62)1.78 (1.11–2.83)
 Highest tertile (>350 μmol/L)4.04 (2.62–6.21)2.62 (1.67–4.10)
Diabetes duration ≥9 years1.75 (1.31–2.35)1.19 (0.86–1.65)
Diabetes medication (vs. none)
 Oral only3.01 (1.78–5.07)2.20 (1.28–3.76)
 Any insulin use5.51 (3.25–9.34)3.00 (1.71–5.28)
eGFR <60 mL/min/1.73 m2 (creatinine)2.00 (1.35–2.97)1.40 (0.92–2.13)
ACR
 30 to <300 mg/g1.51 (1.02–2.24)1.16 (0.78–1.74)
 ≥300 mg/g3.07 (2.00–4.72)1.95 (1.23–3.07)
DSST, per 1 lower race-specific SD1.67 (1.42–1.96)1.57 (1.33–1.84)
  • Values are reported as HR (95% CI). Model 1 included age, sex, and race. Model 2 included all variables in model 1 plus all covariates listed in the table.

  • *Overweight and normal weight were collapsed into one reference group because of the small numbers of normal weight participants.