Table 4

Impact of extreme values of predictor variables on 3-year predicted probabilities of progression to type 2 DM and regression to NGR for adherent participants

Predictor variablesProgressRegress
3-year predicted probabilities (%) if treated with placeboPercent ARR (NNT)3-year predicted probabilities (%) if treated with placeboPercent absolute chance increment (NNT)
Age (years)SexBMI (kg/m2)FG (mg/dL)TG (mg/dL)LifestyleMetforminLifestyleMetformin
40M27996786 (16)1 (82)5725 (4)12 (7)
40M411152454526 (4)14 (7)2022 (4)11 (9)
60M27996786 (16)−2 (—)4524 (4)7 (11)
60M411152454526 (4)6 (16)1518 (5)7 (13)
40F27996786 (14)1 (46)4725 (4)2 (18)
40F411152454728 (3)16 (5)1622 (4)7 (14)
60F27996786 (14)−2 (—)3724 (4)−1 (—)
60F411152454728 (3)8 (10)1218 (5)4 (23)
  • —, not effective; F, woman with history of pregnancy but no history of GDM; FG, fasting glucose; M, male; NNT, number needed to treat.