Table 8.4

Median cost of insulin products in the U.S. calculated as AWP (39) and NADAC (40) per 1,000 units of specified dosage form/product

InsulinsCompoundsDosage form/productMedian AWP (min, max)*Median NADAC (min, max)*
Rapid-acting analogs• LisproU-100 vial;$330$264
U-100 3 mL cartridges;$408$326
U-100 prefilled pen; U-200 prefilled pen$424$339
• AspartU-100 vial;$331$265
U-100 3 mL cartridges;$410$330
U-100 prefilled pen$426$341
• GlulisineU-100 vial;$306$245
U-100 prefilled pen$394$315
• Inhaled insulinInhalation cartridges$725 ($544, $911)N/A
Short-acting analogs• Human RegularU-100 vial$165 ($165, $178)$135 ($135, $145)
Intermediate-acting analogs• Human NPHU-100 vial;$165 ($165, $178)$135 ($135, $145)
U-100 prefilled pen$377$305
Concentrated Human Regular insulin• U-500 Human Regular insulinU-500 vial;$178$143
U-500 prefilled pen$230$184
Basal analogs• GlargineU-100 vial; U-100 prefilled pen; U-300 prefilled pen$298$239 ($239, $241)
• Glargine biosimilarU-100 prefilled pen$253$203
• DetemirU-100 vial; U-100 prefilled pen$323$259
• DegludecU-100 prefilled pen; U-200 prefilled pen$355$285
Premixed insulin products• NPH/Regular 70/30U-100 vial;$165 ($165, $178)$134 ($134, $146)
U-100 prefilled pen$377$305
• Lispro 50/50U-100 vial;$342$278
U-100 prefilled pen$424$339
• Lispro 75/25U-100 vial;$342$273
U-100 prefilled pen$424$340
• Aspart 70/30U-100 vial;$343$275
U-100 prefilled pen$426$341
Premixed insulin/GLP-1 receptor agonist products• Degludec/Liraglutide100/3.6 prefilled pen$763N/A
• Glargine/Lixisenatide100/33 prefilled pen$508$404
  • *AWP or NADAC calculated as in Table 8.3; median listed alone when only one product and/or price.

  • †Not applicable; data not available.