Table 3

Biomarker means taken before follow-up windows with and without clinical events

CKDMA
Event (n = 74)No event (n = 4,313)Event (n = 143)No event (n = 4,244)
sTNFR-12.10 (1.94–2.28)1.50 (1.47–1.54)1.67 (1.57–1.79)1.48 (1.45–1.51)
sTNFR-21.82 (1.70–1.94)1.38 (1.35–1.40)1.51 (1.43–1.59)1.36 (1.34–1.39)
sE-selectin45.3 (39.9–51.3)44.6 (42.8–46.4)51.8 (46.6–57.5)44.0 (42.3–45.9)
PAI-1 active8.64 (7.27–10.26)7.88 (7.61–8.16)9.44 (8.25–10.80)7.75 (7.48–8.03)
PAI-1 total158.2 (140.8–177.8)153.4 (148.8–158.1)166.3 (151.3–182.7)151.9 (147.3–156.6)
sICAM-1293.8 (273.9–315.0)306.9 (300.8–313.0)309.8 (292.7–327.9)306.4 (300.4–312.5)
sVCAM-1879.6 (797.8–969.9)945.4 (917.1–974.5)893.4 (820.3–973.0)948.2 (920.1–977.2)
IL-67.03 (5.96–8.29)6.60 (6.35–6.85)7.36 (6.46–8.38)6.56 (6.31–6.83)
Fibrinogen253.4 (233.9–274.5)220.5 (217.0–224.0)230.0 (215.3–245.8)220.6 (217.1–224.1)
CRP0.21 (0.16–0.28)0.21 (0.19–0.22)0.19 (0.15–0.24)0.21 (0.20–0.23)
  • Data are geometric mean (95% CI). Event count across up to four measurements in 1,396 participants.