Baseline | Slope | ||||
---|---|---|---|---|---|

Predictor | Coefficient | P value | Coefficient | P value | R^{2} decomposition |

Constant | 407.630 | <0.001 | −2.102 | 0.396 | — |

Cystatin C | −11.661 | <0.001 | n.s. | n.s. | 9 |

Endostatin | −2.957 | 0.133 | n.s. | n.s. | <1 |

UMOD | 2.977 | <0.001 | n.s. | n.s. | 4.3 |

CHI3L1 | 1.124 | 0.037 | n.s. | n.s. | <1 |

HGF | 0.047 | 0.949 | 0.463 | 0.044 | <1 |

MMP1 | 0.731 | 0.187 | −0.307 | 0.082 | <1 |

MMP7 | −1.233 | 0.064 | n.s. | n.s. | <1 |

TIE2 | 4.622 | <0.001 | n.s. | n.s. | 3.3 |

TNFR1 | −10.888 | <0.001 | n.s. | n.s. | 12.9 |

KIM1 | −0.064 | 0.922 | −1.084 | <0.001 | 3 |

FGF23 | −0.983 | 0.269 | 0.456 | 0.086 | <1 |

NTproBNP | 0.071 | 0.793 | −0.253 | 0.006 | <1 |

Age (years) | −0.684 | <0.001 | 0.048 | 0.039 | 27 |

Current or former smoker | 2.460 | 0.024 | n.s. | n.s. | <1 |

Mean arterial pressure | 0.085 | 0.087 | n.s. | n.s. | <1 |

Total cholesterol | −0.762 | 0.096 | n.s. | n.s. | <1 |

The model had an adjusted

*R*^{2}of 62.5%. Biomarkers had a total contribution of 34.4%, and clinical risk factors had a total contribution of 28.1%. The decomposition of the model*R*^{2}combines the contributions of baseline and slope coefficients for each predictor. n.s., not selected.