Table 2

Standardized ORs evaluating the risk of undergoing 5y-Relapse and/or remaining in nonremission

Risk of 5y-Relapse compared with 5y-DR*Risk of 5y-NDR compared with 5y-Relapse*Risk of 5y-NDR compared with 5y-DR*
OR95% CIPOR95% CIPOR95% CIP
Baseline variables
 Fasting glucose (mmol/L)1.160.75–1.740.611.410.83–2.550.311.951.34–2.950.002
 HbA1c (%)1.190.78–1.790.534.882.09–13.790.0046.693.5–14.44<0.001
 Number of anti-T2D treatments1.851.19–2.960.043.511.85–7.650.0024.982.98–9.13<0.001
 Insulin usage (yes/no)2.570.61–9.850.3013.694.00–61.98<0.00147.8115.57–187.96<0.001
 Age (years)0.970.63–1.500.962.061.26–3.580.021.891.30–2.850.004
 T2D duration (years)1.480.94–2.350.185.322.32–15.240.0026.733.66–13.93<0.001
 Sex (male/female)1.390.49–3.700.620.790.26–2.480.811.220.52–2.800.70
Kinetic variables during the 1st year
 Weight lost (% baseline)2.661.62–4.660.010.630.37–1.030.131.721.18–2.600.01
 Fat mass lost (% baseline)2.231.25–4.330.040.610.33–1.060.151.310.89–1.970.23
 Fat-free mass lost (% baseline)0.420.21–0.760.041.480.87–2.650.240.640.42–0.950.05
 Trunk fat mass lost (% baseline)0.750.45–1.230.371.030.59–1.800.970.770.51–1.140.24
1-year variables
 Fasting glycemia (mmol/L)1.280.82–1.970.372.171.16–4.750.072.401.60–3.83<0.001
 HbA1c (%)1.010.64–1.561.005.642.40–16.870.0023.632.25–6.31<0.001
 Number of anti-T2D treatments20.50(8.1–72.04)<0.001
Scores
 DiaRem (20)1.111.01–1.220.061.261.14–1.43<0.0011.541.36–1.81<0.001
 Ad-DiaRem (21)1.121–1.270.121.511.28–1.87<0.0011.841.55–2.32<0.001
 5y-Ad-DiaRem1.211.09–1.350.013.211.89–8.53<0.0011.941.57–2.63<0.001
  • The variables were standardized using the following formula: zi = (xi − µ)/σ where µ represents the variable’s mean and σ its SD. Sex and age were included in the regression model. See Supplementary Table 3 for the nonstandardized version of these ORs.

  • *The group of patients that was used as the reference.

  • †Nonstandardized ORs.

  • ‡Changes during the 1st year were calculated using the following formula: [(1-year value) − (baseline value)]/(baseline value) × 100.