Table 2

VVV in FBG as a continuous variable and incident events

Model 1Model 2Model 3Model 4
HR (95% CI)PHR (95% CI)PHR (95% CI)PHR (95% CI)P
All-cause mortality
 SD1.006 (1.001–1.011)0.0101.007 (1.002–1.012)0.0051.007 (1.002–1.012)0.0051.005 (0.998–1.012)0.181
 ASV1.004 (1.00–1.008)0.0351.004 (1.001–1.008)0.0191.004 (1.001–1.008)0.0201.002 (0.997–1.007)0.439
 CV1.015 (1.005–1.025)0.0031.016 (1.006–1.026)0.0021.016 (1.006–1.026)0.0021.013 (1.001–1.026)0.036
 VIM1.015 (1.007–1.024)0.00041.014 (1.006–1.022)0.0011.014 (1.006–1.022)0.001NANA
Cardiovascular events
 SD1.006 (1.002–1.01)0.0021.006 (1.003–1.01)0.00071.006 (1.002–1.01)0.0011.003 (0.997–1.008)0.375
 ASV1.004 (1.001–1.007)0.0031.004 (1.002–1.007)0.0021.004 (1.001–1.007)0.0031.001 (0.997–1.005)0.525
 CV1.01 (1.003–1.018)0.0061.011 (1.003–1.019)0.0051.011 (1.003–1.019)0.0071.005 (0.996–1.014)0.312
 VIM1.006 (0.997–1.014)0.1811.005 (0.997–1.014)0.2101.005 (0.997–1.014)0.232NANA
  • Model 1: includes adjustment for age, race/ethnicity, sex, region of residence, and antihypertensive medication randomization assignment. Model 2: additional adjustment for education, smoking status, BMI, use of aspirin, average cholesterol, eGFR, history of CVD, and use of antihypertensive medications. Model 3: additional adjustment for average SBP. Model 4: additional adjustment for average FBG. NA, not applicable.