Table 2

Differences in regional brain growth dependent on DKA severity

Brain matterRegions contained in clusterVolume (mL)P value*
GMVBilateral postcentral/angular/supramarginal gyri, inferior parietal lobule, bilateral cuneus, precuneus, left middle temporal gyrus68.1<0.001
GMVLeft frontal lobe (superior/middle/inferior frontal gyri and precentral gyrus)33.30.001
GMVLeft bilateral cingulate (anterior/middle)26.50.002
WMVLeft frontal lobe (SFG, MFG, precentral gyrus), left temporal lobe (STG, MTG), left parietal lobe (postcentral/angular/supramarginal gyri, IPL), left occipital lobe (precuneus), as well as cingulum (anterior, middle), corpus callosum, and near left thalamus, left hippocampus, and left caudate95.4<0.001
  • Regions where there is greater growth in those who experienced moderate/severe DKA compared with the none/mild group. IPL, inferior parietal lobe; MTG, middle temporal gyrus; SFG, superior frontal gyrus; STG, superior temporal gyrus.

  • *Statistically significant (P < 0.05).