Table 2

Proportions (95% CI) of those who failed to control* individual risk factors and who failed to control two risk factors simultaneously at 6, 12, and 24 months after second-line ADD initiation

6 months12 months24 months
Individual failure
 HbA1c37 (36–37)39 (39–39)42 (41–42)
 LDL43 (43–43)43 (43–43)42 (41–42)
 Triglycerides46 (45–46)46 (45–46)45 (44–45)
 SBP31 (30–31)31 (30–31)30 (30–30)
Simultaneous failure
 HbA1c + LDL61 (60–61)62 (62–62)63 (62–63)
 HbA1c + SBP53 (53–54)55 (55–55)57 (57–57)
 LDL + SBP57 (56–57)56 (56–57)55 (55–56)
 HbA1c + triglycerides61 (61–61)62 (62–62)63 (62–63)
  • *Control: HbA1c <7.5% (58 mmol/mol); triglycerides <150 mg/dL; and SBP <130/140 mmHg and LDL <70/100 mg/dL for those with/without history of CVD at the time of second-line ADD initiation. LDL, triglycerides, and SBP proportions are calculated among users of lipid-modifying and antihypertensive drugs.