Table 1

Agreement (κ) between glucose pattern classification using five time points as reference and discrimination power (relative entropy) for different combinations of time points

Time points (min)RISC cohortTUEF cohort (external validation)
0306090120κ (95% CI)Relative entropyκ (95% CI)Relative entropy
XX0.41 (0.37–0.45)0.380.46 (0.43–0.49)0.40
XX0.46 (0.42–0.49)0.470.34 (0.31–0.36)0.44
XX0.70 (0.67–0.73)0.630.66 (0.64–0.68)0.58
XXX0.62 (0.58–0.65)0.600.61 (0.59–0.63)0.58
XXX0.75 (0.72–0.77)0.690.71 (0.69–0.73)0.65
XXX0.80 (0.77–0.83)0.710.79 (0.77–0.81)0.69
XXXX0.85 (0.82–0.87)0.740.84 (0.82–0.85)0.73
XXXXX1 (reference)0.791 (reference)0.79
  • κ = 0 means agreement only by chance, while κ = 1 means perfect agreement. Relative entropy is a measure of adequate separation between classes taking values between 0 and 1. Higher relative entropy indicates that individuals can be classified with higher confidence (5).