Table 3

Cox regression models of risk factors for simplex and proliferative retinopathy

ModelRisk factorSimplex retinopathyProliferative retinopathy
PHazard ratio95% CIPHazard ratio95% CI
ASex (women/men)0.550.920.71–1.200.840.950.55–1.62
Onset before puberty<0.0010.570.43–0.770.921.030.57–1.89
Onset during puberty0.380.850.60–1.220.471.280.65–2.50
Onset after pubertyReferenceReference
wHbA1c<0.0011.051.03–1.06<0.0011.101.08–1.12
BSex (women/men)0.730.950.74–1.240.890.960.56–1.65
Onset 0.0–4.9 years0.0010.380.22–0.660.690.770.22–2.77
Onset 5.0–9.9 years0.080.660.42–1.060.921.060.35–3.21
Onset 10.0–14.9 years0.500.850.52–1.380.641.300.43–3.91
Onset 15.0–19.9 years0.940.980.57–1.670.980.990.28–3.52
Onset 20.0–24.9 years0.500.830.49–1.420.830.860.23–3.26
Onset 25.0–29.9 years0.960.990.59–1.660.580.690.18–2.61
Onset 30.0–34.9 yearsReferenceReference
wHbA1c<0.0011.051.04–1.06<0.0011.101.08–1.12
CSex (women/men)0.570.930.71–1.210.951.020.60–1.74
Age at onset<0.0011.031.01–1.040.481.010.98–1.04
wHbA1c ≤5 years0.031.011.00–1.020.310.990.97–1.01
wHbA1c >5 years<0.0011.041.03–1.05<0.0011.121.09–1.14
DSex (women/men)0.740.920.56–1.510.062.540.98–6.56
Age at onset<0.0011.241.14–1.360.041.221.01–1.47
wHbA1c before puberty0.691.010.98–1.030.690.990.95–1.03
wHbA1c during puberty0.321.010.99–1.040.681.010.97–1.05
wHbA1c after puberty0.021.031.01–1.05<0.0011.121.06–1.18