Table 1

Demographic and clinical characteristics of study participants by source registry

DPVWACDD
Total cases (N)59,8832,595
Total observation time (patient-years)296,17916,063
Boys (%)5251
Mean age at diagnosis ± SD (years)8.0 ± 3.88.1 ± 3.9
Mean number of visits/year ± SD (N)3.7 ± 1.83.3 ± 0.8
Mean follow-up time ± SD (years)4.3 ± 3.55.4 ± 3.7
Mean HbA1c ± SD (%)8.0 ± 1.48.4 ± 1.2
Mean HbA1c (mmol/mol)6468
Median HbA1c (IQR) (%)7.8 (7.1–8.7)8.2 (7.5–9.0)
Median HbA1c (IQR) (mmol/mol)62 (54–72)66 (58–75)
SH rate per 100 patient-years (95% CI)*4.0 (3.9, 4.1)10.0 (9.1, 10.9)
Annual percent change in mean SH rate; RR (95% CI)*−2%; 0.983 (0.981, 0.986), P < 0.001−6%; 0.935 (0.934, 0.937), P < 0.001
  • *Poisson regression estimate.