HRV indices in TODAY participants versus obese control subjects
| Variable | TODAY, n = 397 | Obese control subjects, n = 133 | P value | |
|---|---|---|---|---|
| Unadjusted | Adjusted | |||
| SDNN (ms)* | 58.1 ± 29.6 | 67.1 ± 25.4 | <0.0001 | <0.0001 |
| RMSSD (ms)* | 53.2 ± 36.7 | 67.9 ± 35.2 | <0.0001 | <0.0001 |
| PNN50 (%)* | 26.3 ± 23.7 | 39.7 ± 23.0 | <0.0001 | <0.0001 |
| LF Power (n.u.)† | 47.3 ± 20.0 | 39.5 ± 19.7 | 0.0001 | <0.0001 |
| HF Power (n.u.)* | 52.7 ± 20.0 | 60.5 ± 19.7 | 0.0001 | <0.0001 |
| LF:HF ratio† | 1.4 ± 1.7 | 1.0 ± 1.1 | <0.0001 | <0.0001 |
Unadjusted means ± SD are shown in the table. Total power for TODAY participants was 2,576 ± 2,919. P value from general linear model comparing mean of the obese control subjects to the TODAY participants. SDNN, RMSSD, and LF:HF ratio were log transformed prior to testing because of skewed distribution. A nonparametric rank-based test was used to compare the PNN50 values. Unadjusted and adjusted P values for age, sex, race-ethnicity, smoking, and BMI are given for the cardiac autonomic function measures. n.u., normalized units.
↵* Lower = worse.
↵† Higher = worse.