Table 2

Associations of OxGua levels with type 2 diabetes incidence

Modeling (μg/g creatinine)ntotalncasesModel 1aModel 2bModel 3c
Per 1 SDd7,8281,3281.05 (1.01; 1.09)1.04 (1.00; 1.09)1.04 (1.00; 1.09)
≤98.91,565285RefRefRef
>98.9 to ≤130.71,5662460.96 (0.81; 1.15)0.98 (0.82; 1.16)0.98 (0.83; 1.17)
>130.7 to ≤165.21,5662631.06 (0.90; 1.26)1.02 (0.86; 1.21)1.02 (0.86; 1.21)
>165.2 to ≤221.81,5652551.06 (0.89; 1.26)1.03 (0.87; 1.23)1.03 (0.87; 1.23)
>221.81,5662791.21 (1.02; 1.43)1.13 (0.96; 1.34)1.14 (0.96; 1.35)
  • Data are HR (95% CI) unless otherwise indicated. Boldface type indicates statistical significance at P < 0.05. Ref, reference.

  • a Model adjusted for alcohol consumption, triglycerides, and HDL cholesterol.

  • b Model adjusted for BMI, smoking, alcohol consumption, use of antihypertensive medication, systolic blood pressure, HbA1c, triglycerides, HDL cholesterol, eGFR, and family history of diabetes.

  • c Model adjusted for all baseline characteristics shown in Table 1.

  • d 1 SD = 275 μg/g creatinine.