Table 1

Comparison of baseline characteristics by T2D status across cohorts with IPD

Without T2D (n = 29,348)With T2D (n = 2,182)P value
Sex (% women)24,068 (82.0)1,608 (73.7)<0.001
Age years69.0 (9.1)70.0 (8.5)<0.001
Weight kg70.3 (13.2)76.5 (15.1)<0.001
Height cm162.6 (8.9)163.5 (9.7)<0.001
BMI kg/m226.5 (4.2)28.5 (4.7)<0.001
Underweight352 (1.2)11 (0.5)<0.001
Normal weight10,817 (36.8)478 (21.9)
Overweight12,560 (42.8)919 (42.1)
Obese5,619 (19.2)774 (35.5)
FN-BMD T-score (continuous)−1.33 (1.4)−1.05 (1.7)<0.001
FN-BMD T-score clinical categories
 Normal10,299 (35.1)1,021 (46.8)<0.001
 Osteopenia15,067 (51.3)952 (43.6)
 Osteoporosis3,982 (13.6)209 (9.6)
Corticosteroid use1,126 (3.8)115 (5.3)0.03
Antiosteoporotic treatment2,622 (8.9)225 (10.3)0.03
Prevalent VFs3,513 (11.9)228 (10.4)0.03
LS-TBS*1.26 (0.12)1.21 (0.13)<0.001
LS-BMD, g/cm2*1.14 (0.21)1.21 (0.23)<0.001
  • The P value corresponds to t test (continuous variables) or χ2 test (categorical variables) for difference between individuals with and without T2D at baseline.

  • LS-TBS, lumbar spine TBS.

  • * Denotes that information was available only at follow up for 7,819 individuals (n = 7,347 without T2D and n = 472 with T2D).