Table 9.3

Median cost of insulin products in the U.S. calculated as AWP (54) and NADAC (55) per 1,000 units of specified dosage form/product

InsulinsCompoundsDosage form/productMedian AWP (min, max)*Median NADAC (min, max)*
Rapid-acting• Lispro follow-on productU-100 vial$157$126
U-100 prefilled pen$202$162
• LisproU-100 vial$330$264
U-100 3 mL cartridges$408$327
U-100 prefilled pen; U-200 prefilled pen$424$340
• GlulisineU-100 vial$341$273
U-100 prefilled pen$439$353
• AspartU-100 vial$347$278
U-100 3 mL cartridges$430$345
U-100 prefilled pen$447$358
• Inhaled insulinInhalation cartridges$924$606
Short-acting• human regularU-100 vial$165 ($165, $178)††$134 ($134, $146)††
Intermediate-acting• human NPHU-100 vial$165 ($165, $178)††$135 ($135, $146)††
U-100 prefilled pen$377$304
Concentrated human regular insulin• U-500 human regular insulinU-500 vial$178$144
U-500 prefilled pen$230$184
Long-acting• Glargine follow-on productU-100 prefilled pen$261$210
• GlargineU-100 vial; U-100 prefilled pen$340$272
U-300 prefilled pen$346$280
• DetemirU-100 vial; U-100 prefilled pen$370$295
• DegludecU-100 vial; U-100 prefilled pen; U-200 prefilled pen$407$326
Premixed insulin products• NPH/regular 70/30U-100 vial$165 ($165, $178)$134 ($134, $145)
U-100 prefilled pen$377$303
• Lispro 50/50U-100 vial$342$274
U-100 prefilled pen$424$338
• Lispro 75/25U-100 vial$342$274
U-100 prefilled pen$424$340
• Aspart 70/30U-100 vial$360$289
U-100 prefilled pen$447$358
Premixed insulin/GLP-1 RA products• Glargine/Lixisenatide100/33 prefilled pen$565$454
• Degludec/Liraglutide100/3.6 prefilled pen$832$668
  • AWP, average wholesale price; GLP-1, glucagon-like peptide 1; NADAC, National Average Drug Acquisition Cost.

  • * AWP or NADAC calculated as in Table 9.2.

  • Inclusive of both the original and “faster-acting” products.

  • †† AWP and NADAC data presented do not include vials of regular human insulin and NPH available at Walmart for approximately $25/vial; median listed alone when only one product and/or price.