Table 4.3

Assessment of hypoglycemia risk

Factors that increase risk of treatment-associated hypoglycemia
  • Use of insulin or insulin secretagogues (i.e., sulfonylureas, meglitinides)

  • Impaired kidney or hepatic function

  • Longer duration of diabetes

  • Frailty and older age

  • Cognitive impairment

  • Impaired counterregulatory response, hypoglycemia unawareness

  • Physical or intellectual disability that may impair behavioral response to hypoglycemia

  • Alcohol use

  • Polypharmacy (especially ACE inhibitors, angiotensin receptor blockers, nonselective β-blockers)

  • See references 100104.