Table 3

HRs and 95% CI for plasma LA in quintiles and per 5% and incident type 2 diabetes in 3,257 post-MI patients from the Alpha Omega Cohort

Quintiles of plasma LAPer 5%P value
Q1 (n = 652)Q2 (n = 650)Q3 (n = 651)Q4 (n = 653)Q5 (n = 651)P-trend*
Median plasma LA, %43.947.650.152.856.3
Cases4938313122
Model 11.000.76 (0.50, 1.16)0.63 (0.40, 0.98)0.61 (0.39, 0.96)0.42 (0.26, 0.70)<0.0010.73 (0.63, 0.85)<0.001
Model 21.000.74 (0.48, 1.14)0.64 (0.40, 1.00)0.60 (0.38, 0.94)0.44 (0.26, 0.75)0.0010.73 (0.62, 0.86)<0.001
  • * P values for trend were obtained by assigning each patient median plasma LA for the category and this value was modeled as continuous.

  • Model 1 was adjusted for age (continuous; years), sex (men/women), and Alpha Omega Trial treatment code (four categories).

  • Model 2: model 1 plus physical activity (three categories), smoking status (three categories), educational level (four categories), BMI (continuous; kg/m2), family history of type 2 diabetes (yes/no), total energy intake (excluding calories from alcohol, continuous; kcal/day), alcohol intake (four categories), dietary fiber (g/day; continuous), and dietary cholesterol (mg/day; continuous).