Table 2

Univariate analyses in patients with and without diabetes relapse following initial remission after bariatric surgery in training and validating cohorts

Baseline characteristicsCleveland Clinic cohort (n = 425)Three external cohorts (n = 319)
Long-term diabetes remissionLate diabetes relapse after initial remissionPLong-term diabetes remissionLate diabetes relapse after initial remissionP
N289136219100
Female205 (70.9)90 (66.2)0.38148 (68.0)70 (70.0)0.82
Age (years)49.9 ± 10.451.1 ± 9.40.2549.8 ± 8.851.3 ± 9.50.20
BMI (kg/m2)47.7 ± 8.345.2 ± 9.00.00548.0 ± 7.846.4 ± 6.10.046
Duration of diabetes (years)4.2 ± 3.97.0 ± 5.0<0.0013.8 ± 2.76.3 ± 4.0<0.001
Number of diabetes medications1.4 ± 0.82.0 ± 0.9<0.0011.3 ± 0.81.9 ± 1.0<0.001
Insulin use39 (13.5)40 (29.4)<0.00117 (7.8)29 (29.3)<0.001
HbA1c (%)7.0 ± 1.37.7 ± 1.6<0.0016.4 ± 1.07.6 ± 1.5<0.001
HbA1c (mmol/mol)53 ± 14.261 ± 17.5<0.00146 ± 10.960 ± 16.4<0.001
Type of surgery0.0530.040
 SG37 (12.8)28 (20.6)75 (34.2)47 (47.0)
 RYGB252 (87.2)108 (79.4)144 (65.8)53 (53.0)
  • Data are mean ± SD or n (%).