Table 2

Number of events, incidence rate per 10,000 person-years by type, and adjusted HRs comparing GBP and matched control patients for sex, age, BMI, eGFR, and socioeconomic variables, including country of birth

End pointGBP (n = 5,321)Control (n = 5,321)HR (95% CI)P value
Half eGFR (MDRD) (mL/min/1.73 m2)51 (20.43)120 (49.00)0.63 (0.45, 0.89)0.0076
Half eGFR (CKD-EPI) (mL/min/1.73 m2)40 (16.02)105 (42.86)0.58 (0.40, 0.85)0.0046
Macroalbuminuria305 (127.22)575 (252.33)0.55 (0.47, 0.65)<0.0001
Acute kidney failure52 (20.85)74 (30.14)0.57 (0.36, 0.90)0.0147
CKD52 (20.84)114 (46.62)0.45 (0.30, 0.67)0.0001
Diabetic nephropathy17 (6.79)53 (21.59)0.22 (0.10, 0.47)<0.0001
Severe renal disease98 (39.49)187 (76.87)0.50 (0.37, 0.68)<0.0001
Severe renal disease or half eGFR value (MDRD)135 (54.57)260 (107.39)0.56 (0.44, 0.71)<0.0001
Severe renal disease or half eGFR value (CKD-EPI)124 (50.09)245 (101.14)0.54 (0.42, 0.70)<0.0001
Hemodialysis or peritoneal dialysis6 (2.39)27 (10.97)0.25 (0.08, 0.72)0.0104
Kidney transplantation6 (2.39)6 (2.43)0.62 (0.12, 3.39)0.5854
Fatal kidney disease12 (4.79)32 (12.97)0.48 (0.22, 1.04)0.0636
CVD291 (120.10)346 (145.29)0.74 (0.61, 0.89)0.0015
Nonfatal CVD286 (117.91)333 (139.69)0.82 (0.70, 0.97)0.0184
Congestive heart failure86 (34.56)233 (96.40)0.33 (0.24, 0.46)<0.0001
Fatal CVD31 (12.36)93 (37.69)0.36 (0.22, 0.58)<0.0001
All-cause mortality183 (72.90)351 (142.06)0.58 (0.47, 0.72)<0.0001