Table 2

Percentage of the population (95% CI) eligible for glucose-lowering medication treatment according to different HbA1c thresholds among persons meeting the 2019 Endocrine Society definition of diabetes for older adults and standard diagnostic criteria for diabetes, U.S. adults aged 65 years and older with no prior diagnosis of diabetes, NHANES 2005–2016

Treatment thresholdDiabetes by Endocrine Society criteria (n = 398)*Diabetes by standard criteria (n = 188)
Percentage95% CIPercentage95% CI
HbA1c ≥7.0%5.42.5–8.411.85.5–18.0
HbA1c ≥7.5%3.30.9–5.77.12.0–12.3
HbA1c ≥8.0%2.00.0–4.04.4−0.0 to 8.8
HbA1c ≥8.5%1.6−0.3 to 3.53.4−0.7 to 7.6
HbA1c ≥9.0%0.6−0.0 to 1.31.3−0.1 to 2.8
  • * Participants meeting diabetes by the Endocrine Society criteria had HbA1c ≥6.5% (48 mmol/mol), FPG ≥126 mg/dL, or 2-h PG ≥200 mg/dL with prediabetic HbA1c or FPG.

  • Participants meeting diabetes by the standard criteria had HbA1c ≥6.5% (48 mmol/mol) or FPG ≥126 mg/dL.