Table 1

Patients’ characteristics

	CON	SAID	SIDD	SIRD	MOD	MARD
n	83	254	25	61	240	254
Genotype frequency (CC/CG/GG), n	54/24/5	137/105/12	12/13/0	22/33/6	136/91/13	141/95/18
Female sex, n (%)	26 (31)	117 (46)	5 (20)	17 (28)	108 (45)	71 (28)
Age (years)	47 ± 14	37 ± 12	43 ± 12	56 ± 10	45 ± 10	58 ± 7
BMI (kg/m²)	28.2 ± 5.7	25.0 ± 4.3	27.1 ± 3.7	34.5 ± 3.6	34.9 ± 6.3	27.4 ± 3.5
WHR	0.92 ± 0.09	0.88 ± 0.09	0.94 ± 0.06	1.00 ± 0.07	0.97 ± 0.08	0.95 ± 0.07
Fasting blood glucose (mg/dL)	91 ± 15	136 ± 46	187 ± 60	117 ± 21	130 ± 28	123 ± 24
HbA_1c (%)	5.3 ± 0.3^*	6.6 ± 1.2^*	8.8 ± 1.3^*	6.2 ± 0.7	6.5 ± 0.9	6.3 ± 0.7
HOMA-IR (a.u.)	1.48 ± 0.71^*	0.99 ± 0.87^*	1.97 ± 0.98	4.48 ± 1.21	2.77 ± 1.01	1.94 ± 0.75^*
HOMA-B (a.u.)	122 ± 39	46 ± 31^*	39 ± 21^*	170 ± 46	98 ± 37^*	83 ± 30^*
hs-CRP (mg/dL)	0.1 (0.1; 0.2)	0.1 (0.1; 0.2)	0.2 (0.1; 0.4)	0.4 (0.2; 0.6)	0.3 (0.2; 0.7)	0.2 (0.1; 0.3)
Total cholesterol (mg/dL)	205 ± 35	185 ± 38	206 ± 29	197 ± 42	203 ± 44	201 ± 42
LDL cholesterol (mg/dL)	129 ± 33	109 ± 34^*	131 ± 29	123 ± 37	130 ± 37	129 ± 36
HDL cholesterol (mg/dL)	61 ± 18^*	62 ± 18^*	51 ± 12^*	42 ± 9	45 ± 12	51 ± 14^*
Triglycerides (mg/dL)	93 (62; 148)^*	73 (53; 106)^*	149 (79; 205)	176 (119; 239)	140 (97; 193)^*	117 (83; 161)^*
ALT (units/L)	25 ± 11	21 ± 8	26 ± 16	29 ± 13	25 ± 11	24 ± 10
AST (units/L)	28 ± 19^*	23 ± 17^*	34 ± 18	42 ± 17	37 ± 22^*	29 ± 16^*
GGT (units/L)	26 ± 18^*	22 ± 23^*	36 ± 24	49 ± 44	46 ± 62	35 ± 33^*

Data are shown as absolute numbers, percentages, mean ± SD, or median (interquartile range), as applicable. a.u., arbitrary units; ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, γ-glutamyl transferase; HOMA-IR, HOMA of insulin resistance; HOMA-B, HOMA of β-cell function; WHR, waist-to-hip ratio.
↵* P < 0.05 vs. SIRD (Dunnett test).