Table 2

Summary of rates of hypoglycemia (baseline to week 26)

Lispro, N = 337 Rate (events/patient/year)URLi, N = 336 Rate (events/patient/year)Relative rate URLi/lispro (95% CI)
Severe hypoglycemia0.040.020.58 (0.14, 2.50)
Documented hypoglycemia7.437.571.02 (0.81, 1.28)
Nocturnal hypoglycemia0.530.681.29 (0.82, 2.03)
Postmeal hypoglycemia (h)
 0–11.541.761.14 (0.75, 1.74)
 0–21.862.471.33 (0.92, 1.92)
 0–42.583.51*1.36 (1.01, 1.83)*
 >41.151.100.95 (0.61, 1.48)
  • Data are LSM unless otherwise stated. Hypoglycemia was defined as SMBG <3.0 mmol/L (54 mg/dL) for documented, nocturnal, and postmeal hypoglycemia. For postmeal hypoglycemia, patient reported timing in relation to meal.

  • * P < 0.05 for between-treatment group comparisons.