Table 2

Summary of efficacy and tolerability with long-acting GLP-1 receptor agonists

LiraglutideExenatide LARTaspoglutideAlbiglutideLY2189265
Change in A1C (%)−1.1 to −1.6−1.9−1.2−0.9−1.5
Change in body weight (kg)−0.2 to −3.2−3.7−2.8−1.4−2.5
Change in SBP (mmHg)−2.3 to −6.7−4.7Not reported−5.8−5.1
Nausea (%)7–2926.45225.813
Vomiting (%)4.4–1710.82212.9Not reported
  • Data are from the following references: 24, 2732, 3639, 41, and 43.