Table 1

Baseline demographic and disease characteristics

CANA100/MET (n = 237)CANA300/MET (n = 237)CANA100 (n = 237)CANA300 (n = 238)MET (n = 237)Total (N = 1,186)
Sex, n (%)
 Male108 (45.6)115 (48.5)105 (44.3)125 (52.5)116 (48.9)569 (48.0)
 Female129 (54.4)122 (51.5)132 (55.7)113 (47.5)121 (51.1)617 (52.0)
Age, years54.2 ± 9.655.4 ± 9.854.0 ± 10.755.8 ± 9.655.2 ± 9.854.9 ± 9.9
Race, n (%)
 White189 (79.7)187 (78.9)192 (81.0)208 (87.4)192 (81.0)968 (81.6)
 Black/African American6 (2.5)8 (3.4)12 (5.1)8 (3.4)9 (3.8)43 (3.6)
 Asian6 (2.5)5 (2.1)4 (1.7)4 (1.7)9 (3.8)28 (2.4)
 Other36 (15.2)37 (15.6)29 (12.2)18 (7.6)27 (11.4)147 (12.4)
HbA1c, %8.8 ± 1.18.9 ± 1.28.8 ± 1.28.8 ± 1.28.8 ± 1.28.8 ± 1.2
HbA1c, mmol/mol73 ± 1274 ± 1373 ± 1373 ± 1373 ± 1373 ± 13
Baseline HbA1c, n (%)
 <9.0% (<75 mmol/mol)135 (57.0)137 (57.8)144 (60.8)142 (59.7)146 (61.6)704 (59.4)
 ≥9.0% (≥75 mmol/mol)102 (43.0)100 (42.2)93 (39.2)96 (40.3)91 (38.4)482 (40.6)
FPG, mg/dL191 ± 51202 ± 56196 ± 54193 ± 52191 ± 49195 ± 52
FPG, mmol/L10.6 ± 2.811.2 ± 3.110.9 ± 3.010.7 ± 2.910.6 ± 2.710.8 ± 2.9
Body weight, kg88.3 ± 17.691.4 ± 21.490.2 ± 18.693.0 ± 19.992.1 ± 20.191.0 ± 19.6
BMI, kg/m231.9 ± 5.332.8 ± 6.532.4 ± 5.432.6 ± 5.833.0 ± 6.032.5 ± 5.8
eGFR, mL/min/1.73 m289 ± 1987 ± 1990 ± 1985 ± 1887 ± 1988 ± 19
Type 2 diabetes duration, years2.9 ± 3.33.3 ± 3.93.5 ± 4.43.3 ± 4.43.3 ± 4.53.3 ± 4.1
  • Data are mean ± SD unless otherwise indicated.

  • †Percentages may not total 100.0% due to rounding.

  • ‡Includes American Indian or Alaskan Native, multiple, other, unknown, and not reported.