Table 2

Demographic adjusted* rates of all-cause hospitalization per 1,000 person-years (95% CI) by baseline (1990–1992) diabetes and HbA1c category from negative binomial models: the ARIC study, 1990–2011

No history of diagnosed diabetesDiagnosed diabetesPinteraction§
HbA1c <5.7%HbA1c 5.7 to <6.5%HbA1c ≥6.5%HbA1c <7.0%HbA1c ≥7.0%
n9,2672,441553422839
Total hospitalizations, n24,9728,6682,2212,1135,098
Total person-years169,98341,6419,1906,77911,848
Overall163 (158–169)217 (206–228)**254 (226–281)**340 (297–384)**504 (462–547)**
By race0.011
 White161 (156–166)223 (209–238)**263 (225–302)**297 (249–345)**473 (423–524)**
 Black170 (155–185)209 (191–227)**251 (211–291)**433 (347–519)**552 (481–622)**
By sex0.020
 Men186 (178–195)248 (230–266)**279 (231–327)**397 (316–477)**481 (424–537)**
 Women146 (140–153)195 (180–209)**236 (203–269)**301 (253–350)**518 (459–578)**
By baseline age0.141
 ≤55 years118 (111–124)163 (148–178)**181 (145–217)**280 (215–346)**416 (356–477)**
 >55 years209 (201–218)270 (254–287)**329 (287–372)**405 (345–465)**599 (539–658)**
  • *Adjusted for age, sex, race/center, and insurance status.

  • **P < 0.05, compared with HbA1c <5.7% (reference).

  • P < 0.05, HbA1c ≥7.0 vs. <7.0% (reference).

  • §Multiplicative interaction term.